Figures & data
Figure 1. Molecular mechanisms whereby alterations in miR-15, miR-16, and miR-21 result in aberrant TGF-β signaling. Hematoxylin and Eosin staining of patient tissues is reported. BCL-2, B-cell lymphoma; CXCR-4, C-X-C chemokine receptor type 4; CYC D1, cyclin D1; IHH, Indian hedgehog; IL-11, Interleukin 11; RUNX-2, Runt-related transcription factor 2; RANKL, Receptor activator of nuclear factor kappa-B ligand; TGF-β, Transforming growth factor β; WNT-3A, Wingless-Type MMTV Integration Site Family, Member 3A.
![Figure 1. Molecular mechanisms whereby alterations in miR-15, miR-16, and miR-21 result in aberrant TGF-β signaling. Hematoxylin and Eosin staining of patient tissues is reported. BCL-2, B-cell lymphoma; CXCR-4, C-X-C chemokine receptor type 4; CYC D1, cyclin D1; IHH, Indian hedgehog; IL-11, Interleukin 11; RUNX-2, Runt-related transcription factor 2; RANKL, Receptor activator of nuclear factor kappa-B ligand; TGF-β, Transforming growth factor β; WNT-3A, Wingless-Type MMTV Integration Site Family, Member 3A.](/cms/asset/a9a67490-2e55-40e7-a205-a31832a2236d/kmco_a_1109744_f0001_oc.gif)