Figures & data
Figure 1. The potential mechanism through which circRNA zinc finger protein 609(circZNF609) regulates mRNA stability. CircZNF609 contains several binding sites for ELAV like RNA binding protein 1 (ELAVL1). The circRNA interaction with the cytoskeleton-associated protein 5 (CKAP5) transcript favours the binding of ELAVL1 to the mRNA, increasing mRNA levels and translation. Lack of circZNF609 or disruption of the circZNF609-mRNA interaction will impair mRNAstability and translation of CKAP5 protein leading to altered microtubules (MT)dynamics.
