Abstract
In the present study silver nanoparticles were synthesized from Elaeodendron croceum stem bark and leaf extracts (ECB-AgNPs and ECL-AgNPs respectively) and were characterized using UV-visible spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction and transmission electron microscopy. The antioxidant activity was determined by evaluating the effect on DPPH and ABTS. The activities against selected Gram negative and Gram-positive bacteria as well as MCF-7 and MDA-MB-231 cells were also carried out. The nanoparticles obtained were stable aqueous dispersive, crystalline, and spherical shaped with average particle size of 22.26 nm and 10.01 nm for ECB-AgNPs and ECL-AgNPs respectively. The X-ray Diffraction (XRD) patterns revealed four diffraction peaks at 32.24°, 48.11°, 58.64°, and 77.47° that was indexed to (111), (200), (220), and (311) planes fcc. However, the minimum inhibitory concentrations and IC50 values were higher than the standards used. In summary, a single step method of synthesizing silver nanoparticles from Elaeodendron croceum stem bark and leaf is reported and may serve as potential source of antimicrobial and anticancer agents.
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Acknowledgments
In loving memory of Dr Emmanuel Olusegun Ajayi who passed on to Glory. We acknowledge his contribution to this work and MPED Research Center.
Disclosure statement
No potential conflict of interest was reported by the author(s).