Neutrophil/lymphocyte and platelet/lymphocyte ratios in all mood states of bipolar disorder

Figures & data

Table 1. Characteristics of groups.

	Manic (n = 79) Mean ± SD	Depressed (n = 61) Mean ± SD	Euthymic (n = 59) Mean ± SD	Control (n = 86) Mean ± SD	p
Age (years)	36.43 ± 10.10	38.75 ± 8.49	38.63 ± 11.84	36.38 ± 8.84	.300*
Gender
Female	43 (54.43%)	32 (52.46%)	28 (47.46%)	43 (50.0%)	.862**
Male	36 (45.57%)	29 (47.54%)	31 (52.54%)	43 (50.0%)
Duration of disease (years)	11.01 ± 9.07	8.18 ± 6.65	8.99 ± 8.09		.355*
Number of hospitalization	4.43 ± 3.22	3.51 ± 2.46	2.85 ± 2.44		.002*

*Kruskal–Wallis test, **χ² test; SD, standard deviation.

Table 2. Laboratory findings of subjects.

	Manic (n = 79) Mean ± SD	Depressed (n = 61) Mean ± SD	Euthymic (n = 59) Mean ± SD	Control (n = 86) Mean ± SD	p^1	p^2	p^3
NLR^a^,^b^,^c^,*	2.23 ± 1.14	2.07 ± 0.98	2.22 ± 1.21	1.52 ± 0.47	.000	.000	.001
PLR^d^,^e^,^f^,*	114.64 ± 43.48	108.28 ± 55.91	119.76 ± 61.73	102.59 ± 29.15	.184	.638	.257
Neutrophil** (µl)	4.63 ± 1.41	4.56 ± 1.30	4.45 ± 1.37	3.73 ± 0.88	.000	.000	.003
Lymphocyte* (µl)	2.27 ± 0.54	2.49 ± 0.83	2.34 ± 0.79	2.55 ± 0.65	.003	.444	.025
Platelet* (µl)	245.84 ± 65.96	238.86 ± 77.53	245.20 ± 68.71	250.73 ± 52.90	.324	.192	.269

^ap = .579 manic vs. depressive, ^bp = .742 manic vs. euthymic, ^cp = .801 depressive vs. euthymic, ^dp = .189 manic vs. depressive, ^ep = .997 manic vs. euthymic, ^fp = .281 depressive vs. euthymic, p¹: manic vs control, p²: depressive vs control, p³: euthymic vs. control, *Mann–Whitney U test, **Student’s t test, SD, standard deviation, p < .05 statistically significant.