Simple peripheral markers for inflammation in adolescents with major depressive disorder

Figures & data

Table 1. Socio-demographic characteristics of the participants.

	Patient group	Control group	P
	n (%)	n (%)
Gender
Male	32 (31.1)	19 (46.3)	.084
Female	71 (68.9)	22 (53.7)
Age	15.64 ± 1.28	15.24 ± 1.17	.090
BMI	20.24 ± 3.19	19.77 ± 3.26	.508

Note: BMI: body mass.

Table 2. Laboratory findings for the patient and control group participants.

Variables	Patient group		Control group		t	P
	M	SD	M	SD
NLR	2.00	0.80	1.63	0.64	2.589	.011*
PLR	120.17	38.13	123.11	30.34	−0.441	.660
MPV (fL)	10.25	0.91	9.62	1.23	2.900	.005*
RDW (%)	13.27	1.97	13.56	0.82	−0.878	.382
WBCs (10^3/μL)	8.28	1.94	7.28	1.81	2.840	.005*
Neutrophils (10^3/μL)	4.93	1.61	4.04	1.55	3.024	.003*
Lymphocytes (10^3/μL)	2.60	0.68	2.55	0.56	0.457	.648
Haemoglobin (g/dL)	14.58	1.89	14.36	1.29	0.674	.501
RBCs (10^6/μL)	5.19	0.66	5.33	0.38	−2.167	.030**
HCT (%)	43.18	6.01	42.78	3.25	−1.100	.271
MCV (fL)	83.97	5.88	80.70	4.49	3.208	.002*
MCH (pg)	27.72	3.78	27.10	1.93	−3.250	.001**
MCHC (g/dL)	33.30	1.53	33.55	1.09	−0.971	.333
Platelets (10^3/μL)	296.04	72.58	302.63	57.01	−0.520	.604
PCT (%)	0.31	0.19	0.38	0.51	−0.279	.780

Notes: The data are expressed as the mean ± standard deviation. HC T: haematocrit; MCH: mean corpuscular haemoglobin; MCHC: mean corpuscular haemoglobin concentration; MCV: mean corpuscular volume; MPV: mean platelet volume; NLR: neutrophil-to-lymphocyte ratio; PCT: plateletcrit; PLR: platelet-to-lymphocyte ratio; RBC: red blood cell; RDW: red cell distribution width; WBC: white blood cell.

*Student’s t-test.

**Mann–Whitney U-test.

Table 3. Pearson’s correlation coefficients for each pair of variables.

	1	2	3	4	5
1. CDI scores	–
2. NLR	0.229**	–
3. PLR	−0.035	0.413**	–
4. MPV	0.185*	0.119	−0.223**	–
5. RDW	0.013	−0.002	−0.096	−0.087	–

Notes: Pearson correlation r scores are expressed in the table. CDI: child depression inventory; MPV: mean platelet volume; NLR: neutrophil-to-lymphocyte ratio; PLR: platelet-to-lymphocyte ratio; RDW: red cell distribution width.

*Correlation is significant at the 0.05 level (two-tailed).

**Correlation is significant at the 0.01 level (two-tailed).