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Articles

Robust dynamic risk prediction with longitudinal studies

ORCID Icon, , &
Pages 159-170 | Received 21 Mar 2017, Accepted 31 Oct 2017, Published online: 27 Nov 2017

Figures & data

Figure 1. Data structure.

Figure 1. Data structure.

Figure 2. Average of estimates, average of the standard error estimates (ASE), empirical standard errors (ESE) and empirical coverage probabilities (CovP) of the 95% CI. One measurement at baseline. Each entry is based on 1000 simulated samples.The x-axis in all the plots is age.

Figure 2. Average of estimates, average of the standard error estimates (ASE), empirical standard errors (ESE) and empirical coverage probabilities (CovP) of the 95% CI. One measurement at baseline. Each entry is based on 1000 simulated samples.The x-axis in all the plots is age.

Figure 3. Age-specific AUCs for the proposed method (age-specific) and cox model (Cox). Values are averaged over 1000 repetitions with sample size n = 5000.

Figure 3. Age-specific AUCs for the proposed method (age-specific) and cox model (Cox). Values are averaged over 1000 repetitions with sample size n = 5000.

Figure 4. Average of estimates, average of the standard error estimates (ASE), empirical standard errors (ESE) and empirical coverage probabilities of the 95% CI. Longitudinal measurements. Each entry is based on 1000 simulated samples. The x-axis in all the plots is age.

Figure 4. Average of estimates, average of the standard error estimates (ASE), empirical standard errors (ESE) and empirical coverage probabilities of the 95% CI. Longitudinal measurements. Each entry is based on 1000 simulated samples. The x-axis in all the plots is age.

Figure 5. Age-specific AUC for the proposed method (age-specific) and JM with longitudinal measurements. Values are averaged over 1000 repetitions with sample size n = 5000.

Figure 5. Age-specific AUC for the proposed method (age-specific) and JM with longitudinal measurements. Values are averaged over 1000 repetitions with sample size n = 5000.

Figure 6. Data analysis: Framingham Heart Study. The panels (a) and (b) show the point and interval estimates of the age-specific effects of the major risk factors for male and female, respectively. The panel (c) shows the point and interval estimates of the age-specific AUC for male and female, respectively.

Figure 6. Data analysis: Framingham Heart Study. The panels (a) and (b) show the point and interval estimates of the age-specific effects of the major risk factors for male and female, respectively. The panel (c) shows the point and interval estimates of the age-specific AUC for male and female, respectively.

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