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HIV Research & Clinical Practice Volume 21, 2020 - Issue 6
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Article

Associations of menopausal age with virological outcomes and engagement in care among women living with HIV in the UK

Hajra Okhai1 Institute for Global Health, University College London, London, UK;2 National Institute for Health Research (NIHR), Health Protection Research Unit (HPRU) in Blood-borne and Sexually Transmitted Infections, University College London, UK;Correspondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0549-4914View further author information
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Shema Tariq1 Institute for Global Health, University College London, London, UKORCID Iconhttps://orcid.org/0000-0001-9802-7727View further author information
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Fiona Burns1 Institute for Global Health, University College London, London, UK;3 Royal Free London NHS Foundation Trust, London, UKView further author information
,
Yvonne Gilleece4 Brighton & Sussex University Hospitals NHS Trust, Brighton, UK;5 Brighton & Sussex Medical School, Brighton, UKORCID Iconhttps://orcid.org/0000-0002-9960-5389View further author information
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Rageshri Dhairyawan6 Department of Infection and Immunity, Barts Health NHS Trust, London, UKView further author information
,
Teresa Hill1 Institute for Global Health, University College London, London, UKORCID Iconhttps://orcid.org/0000-0003-1653-7155View further author information
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Caroline A. Sabin1 Institute for Global Health, University College London, London, UK;2 National Institute for Health Research (NIHR), Health Protection Research Unit (HPRU) in Blood-borne and Sexually Transmitted Infections, University College London, UK;ORCID Iconhttps://orcid.org/0000-0001-5173-2760View further author information
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Pages 174-181 | Received 09 Sep 2020, Accepted 14 Nov 2020, Published online: 08 Dec 2020

Figures & data

Table 1 Demographic and clinical characteristics at time of entry to UK CHIC of the heterosexual women included in the study, overall and stratified by age group at study entry

Table 2 Follow-up time (person-years) contributed by women included in the study with different demographic and clinical characteristics, overall and percentage stratified by age group

Figure 1 Crude and adjusted odds/hazard ratio of engagement in care*, time to viral suppression and viral rebound* at peri- and post-menopausal age compared to pre-menopausal age. Adjusted for ethnicity, ever started cART, previous AIDS, HBV/HCV, calendar year, CD4+ T-cell count, HIV viral load. CI, confidence intervals; 1logistic regression; 2Cox proportional hazard model; * time-updated covariates.

Figure 1 Crude and adjusted odds/hazard ratio of engagement in care*, time to viral suppression and viral rebound* at peri- and post-menopausal age compared to pre-menopausal age. Adjusted for ethnicity, ever started cART, previous AIDS, HBV/HCV, calendar year, CD4+ T-cell count, HIV viral load. CI, confidence intervals; 1logistic regression; 2Cox proportional hazard model; * time-updated covariates.

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