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All Life Volume 13, 2020 - Issue 1
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Cancer Biology

Clinicopathological significance of VEGF and pAkt expressions in oral squamous cell carcinoma

Ali Yousif Babikera Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia;b Department of Histopathology and Cytology, College of Medical Laboratories Science, University of Sciences and Technology, Omdurman, SudanView further author information
,
Saleh A. Almatroodia Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi ArabiaView further author information
,
Ahmad Almatroudia Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi ArabiaView further author information
,
Faris Alrumaihia Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi ArabiaView further author information
,
Mohamed S Abdalazizb Department of Histopathology and Cytology, College of Medical Laboratories Science, University of Sciences and Technology, Omdurman, SudanView further author information
,
Mohammed A. Alsahlia Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi ArabiaView further author information
&
Arshad Husain Rahmania Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi ArabiaCorrespondence[email protected]
View further author information
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Pages 507-515 | Received 21 May 2020, Accepted 22 Aug 2020, Published online: 09 Sep 2020

Figures & data

Figure 1. Haematoxylin and eosin staining a: Oral cancer b: Inflammatory lesion.

Figure 1. Haematoxylin and eosin staining a: Oral cancer b: Inflammatory lesion.

Figure 2. Immunohistochemical staining a: pAkt showed cytoplasmic expression in oral cancer b:pAkt expression was negative in oral cancer c: Inflammatory lesion did not express pAkt.

Figure 2. Immunohistochemical staining a: pAkt showed cytoplasmic expression in oral cancer b:pAkt expression was negative in oral cancer c: Inflammatory lesion did not express pAkt.

Table 1. pAkt expression pattern and its association with clinicopathological findings.

Figure 3. Immunohistochemical staining a: VEGF showed cytoplasmic expression in oral cancer b: VEGF expression was negative in oral cancer c: Inflammatory lesion did not show any expression.

Figure 3. Immunohistochemical staining a: VEGF showed cytoplasmic expression in oral cancer b: VEGF expression was negative in oral cancer c: Inflammatory lesion did not show any expression.

Table 2. VEGF expression pattern and its association with clinical parameters of oral cancer cases.

Figure 4. TUNEL staining a: apoptosis seen in oral cancer b: apoptosis expression was negative in oral cancer.

Figure 4. TUNEL staining a: apoptosis seen in oral cancer b: apoptosis expression was negative in oral cancer.

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