Abstract
This study describes the influence of age, sex, and working memory (WM) performance on the visuospatial WM network. Thirty-nine healthy children (7–12 years) completed a dot location functional magnetic resonance imaging (fMRI) task. Percent signal change measured the intensity and laterality indices measured the asymmetry of activation in frontal and parietal brain regions. Old children showed greater intensity of activation in parietal regions than young children but no differences in lateralization were observed. Intensity of activation was similar across sex and WM performance groups. Girls and high WM performers showed more right-sided lateralization of parietal regions than boys and low WM performers.
ACKNOWLEDGMENTS
The authors gratefully acknowledge the contributions of Caroline Benninger for her help with scanning the children, Martin Zbinden for his ongoing technical support, and Marko Wilke for his assistance with data processing and analysis.
This work was funded by project grants and fellowships from the Swiss Science Foundation (PZ00P1_126309 and IZK0Z1_137130). None of the authors have any conflict of interest.