Abstract
Primaquine, an antimalarial drug, presents a well‐defined oxidation peak around +0.6 V vs SCE at a glassy carbon electrode that can be used for its determination. Calibration graphs were obtained for primaquine in B‐R buffer pH 4.0 from 3.00×10−5 mol L−1 to 1.00×10−2 mol L−1 using linear‐scan voltammetry and 3.00×10−5 mol L−1 to 1.00×10−4 mol L−1 using differential pulse or square‐wave voltammetry. The correspondent detection limits was 9.4 µg mL−1; 4.2 and 1.8 µg mL−1, respectively. All the voltammetric methods were applied with success in direct determination of the primaquine in commercial tablets without separation or extraction procedures.
The authors gratefully acknowledge the financial support of FAPESP and CNPq.