BONE TISSUE CULTURES: AN IN VITRO MODEL FOR THE EVALUATION OF BONE DEFECT HEALING AFTER L-ARGININE AND L-LYSINE ADMINISTRATION

Figures & data

Figure 1. ALP detected in culture medium in control group and Arg-Lys group bone cultures.

Figure 2. Calcium contents in control group and Arg-Lys group bone cultures.

Figure 3. Nitric Oxide values in control group and Arg-Lys group bone cultures.

Table 1. Histomorphometric Measurements of Bone Healing in Defect Treated with Arg-Lys and Control Group

Group	Basal Defect Area (mm^2)	Final Defect Area (mm^2)	Healing %
Control	3.8	3.5 ± 0.11	7.9
Arg-Lys	3.8	2.8 ± 0.32	26.3

Table 2. Microhardness Evaluation (Vickers Degree) of Newly Mineralized Bone in the Healing Area of the Femur Defect Both in Treated and in Control Groups. Data Are Compared with Values of the Pre-existing Bone (Measurements Taken at Least at 1 mm from the Defect)

Group	Pre-existing Bone	Newly Formed Bone
Control	62.2 ± 6.1	57.8 ± 6.2
Arg-Lys	62.8 ± 5.2	60.5 ± 4.6