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Original

SPLENIC CLEARANCE MECHANISMS OF REHYDRATED, LYOPHILIZED PLATELETS

, Ph.D., , , , , , , Ph.D., , M.D. & , Ph.D. show all
Pages 439-451 | Published online: 11 Jul 2009

Figures & data

Table 1. Mechanisms for Retention and Phagocytosis in the Spleen

Figure 1. Circulation kinetics of RL platelets with and without (Gd treated) RES macrophages.

Figure 1. Circulation kinetics of RL platelets with and without (Gd treated) RES macrophages.

Figure 2. Fluorescence microscopy of RL platelets in slenic sinus.

Figure 2. Fluorescence microscopy of RL platelets in slenic sinus.

Figure 3. In vitro microphage phagocytosis of RL platelets.

Figure 3. In vitro microphage phagocytosis of RL platelets.

Figure 4. IV IgG prolongs circulation.

Figure 4. IV IgG prolongs circulation.

Figure 5. Anti-RL platelet IgG is pre-existing in the circulation. 1. RL platelets bind approximately three times more IgG than fresh platelets when incubated with pre-infusion serum. 2. The amount of IgG that binds to each RL platelet is heterodispersed. Flow Cytometric Histograms from Dog X14 Serum incubated with RL or Fresh Platelets.

Figure 5. Anti-RL platelet IgG is pre-existing in the circulation. 1. RL platelets bind approximately three times more IgG than fresh platelets when incubated with pre-infusion serum. 2. The amount of IgG that binds to each RL platelet is heterodispersed. Flow Cytometric Histograms from Dog X14 Serum incubated with RL or Fresh Platelets.

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