Figures & data
Figure 1. The hemodynamic effects of endotoxemia in swine with and without dopamine (DA) resuscitation and DCLHb and hetastarch (HETA) salvage. Pigs were administered LPS. Group I pigs received no treatment. In treatment Groups II and III, DA was administered when “sepsis” developed (≥30% decline in MAP). When “dopamine resistance” occurred (20 μg/kg/min failed to restore MAP to baseline), hetastarch (Group II) and DCLHb (Group III) were added. Time 0=pre-LPS infusion. Values are mean±SEM. Only comparisons of CI were significantly different (p≤0.05).
Figure 2. The hemodynamic effects of DCLHb vs. hetastarch in DA-resistant shock. “BL” (pre-LPS infusion), “SEP” (“sepsis”) (pre-DA infusion), “DR 0” (“dopamine resistance”) (DR-new time 0). Values are mean±SEM. Only comparisons of HR and MPAP were significantly different (p≤0.05).
