Polyhemoglobin–Tyrosinase, an Oxygen Carrier with Murine B16F10 Melanoma Suppression Properties: A Preliminary Report

Binglan Yu Artificial Cells and Organs Research Center and MSSS-FRSQ Research Group (d’equipe) on Blood Substitutes in Transfusion Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada

, Ph.D. &

Professor Thomas Ming Swi Chang Artificial Cells and Organs Research Center and MSSS-FRSQ Research Group (d’equipe) on Blood Substitutes in Transfusion Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, CanadaCorrespondence[email protected]

, O.C., M.D., C.M., Ph.D., F.R.C.P.(C), F.R.S.(C)

Figures & data

Table 1. B16F10 melanoma cell numbers (1 × 10⁵) in cell culture after the addition of saline, PolyHb, free tyrosinase or PolyHb-tyrosinase to the medium

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Table 2. Tumor growth (mm³) of B16F10 melanoma in mice. Sham control group: no intravenous injection; saline group: 0.1 mL intravenous saline daily; (PolyHb-tyrosinase group: 0.l mL intravenous PolyHb-tyrosinase daily. All values are represented as mean ± SEM

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Polyhemoglobin–Tyrosinase, an Oxygen Carrier with Murine B16F10 Melanoma Suppression Properties: A Preliminary Report

Table 1. B16F10 melanoma cell numbers (1 × 10⁵) in cell culture after the addition of saline, PolyHb, free tyrosinase or PolyHb-tyrosinase to the medium

Table 2. Tumor growth (mm³) of B16F10 melanoma in mice. Sham control group: no intravenous injection; saline group: 0.1 mL intravenous saline daily; (PolyHb-tyrosinase group: 0.l mL intravenous PolyHb-tyrosinase daily. All values are represented as mean ± SEM

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Polyhemoglobin–Tyrosinase, an Oxygen Carrier with Murine B16F10 Melanoma Suppression Properties: A Preliminary Report

Figures & data

Table 1. B16F10 melanoma cell numbers (1 × 105) in cell culture after the addition of saline, PolyHb, free tyrosinase or PolyHb-tyrosinase to the medium

Table 2. Tumor growth (mm3) of B16F10 melanoma in mice. Sham control group: no intravenous injection; saline group: 0.1 mL intravenous saline daily; (PolyHb-tyrosinase group: 0.l mL intravenous PolyHb-tyrosinase daily. All values are represented as mean ± SEM

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Table 1. B16F10 melanoma cell numbers (1 × 10⁵) in cell culture after the addition of saline, PolyHb, free tyrosinase or PolyHb-tyrosinase to the medium

Table 2. Tumor growth (mm³) of B16F10 melanoma in mice. Sham control group: no intravenous injection; saline group: 0.1 mL intravenous saline daily; (PolyHb-tyrosinase group: 0.l mL intravenous PolyHb-tyrosinase daily. All values are represented as mean ± SEM