Abstract
The construction of an enantioselective, potentiometric membrane electrode (EPME) based on carbon paste impregnated with macrocyclic antibiotic vancomycin (VCM) as chiral selector is described. The proposed electrode was applied for the assay of S‐perindopril (S‐Pdp) raw material and from its pharmaceutical formulation (Coversyl® tablets) by use of a direct potentiometric method. The surfaces of the electrode can easily be renewed by simply polishing on an alumina paper.
Acknowledgments
The authors thank Claude Harris Leon Foundation and the National Research Foundation (NRF) of South Africa for their financial support.