Bridging the Gap: Using Triangulation Methodology to Estimate Minimal Clinically Important Differences (MCIDs)

Nancy Kline Leidy MEDTAP International, 7101 Wisconsin Avenue, Suite 600, Bethesda, Maryland, 20814, USA; MEDTAP International, 7101 Wisconsin Avenue, Suite 600, Bethesda, MD, 20814, USA

, Ph.D. &

Kathleen W Wyrwich Departments of Research Methodology and Health Services Research, Saint Louis University, 3750 Lindell Boulevardd, McGannon Hall, Room 230, St. Louis, Missouri, 63108, USA

, Ph.D.

Figures & data

Table 1. Baseline Demographic and Clinical Characteristics of Study Samples by Data Source.

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Figure 1. Mean breathlessness diary score by disease severity and studyFootnote^a.

Figure 2. Mean breathlessness diary score by rescue medication use and studyFootnote^b.

Table 2. Change from Baseline to End of Study in Mean Breathlessness Diary Scores by Physician Rating of Efficacy, Juxtaposed with Mean Change in SGRQ, FEV₁, and Statistical Indicators of Magnitude (N = 2,971).

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Bridging the Gap: Using Triangulation Methodology to Estimate Minimal Clinically Important Differences (MCIDs)

Table 1. Baseline Demographic and Clinical Characteristics of Study Samples by Data Source.

Table 2. Change from Baseline to End of Study in Mean Breathlessness Diary Scores by Physician Rating of Efficacy, Juxtaposed with Mean Change in SGRQ, FEV₁, and Statistical Indicators of Magnitude (N = 2,971).

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Bridging the Gap: Using Triangulation Methodology to Estimate Minimal Clinically Important Differences (MCIDs)

Figures & data

Table 1. Baseline Demographic and Clinical Characteristics of Study Samples by Data Source.

Table 2. Change from Baseline to End of Study in Mean Breathlessness Diary Scores by Physician Rating of Efficacy, Juxtaposed with Mean Change in SGRQ, FEV1, and Statistical Indicators of Magnitude (N = 2,971).

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Table 2. Change from Baseline to End of Study in Mean Breathlessness Diary Scores by Physician Rating of Efficacy, Juxtaposed with Mean Change in SGRQ, FEV₁, and Statistical Indicators of Magnitude (N = 2,971).