EFFECTS OF OPUNTIA MEGACANTHA LEAVES EXTRACT ON RENAL ELECTROLYTE AND FLUID HANDLING IN STREPTOZOTOCIN (STZ)-DIABETIC RATS

P. T. Bwititi Departments of Medical Laboratory Sciences, Medical School, University of Zimbabwe, P.O. Box MP 167, Mt. Pleasant, Harare, Zimbabwe

T. Machakaire Departments of Medical Laboratory Sciences, Medical School, University of Zimbabwe, P.O. Box MP 167, Mt. Pleasant, Harare, Zimbabwe

C. B. Nhachi Departments of Clinical Pharmacology, Medical School, University of Zimbabwe, P.O. Box MP 167, Mt. Pleasant, Harare, Zimbabwe

C. T. Musabayane Departments of Physiology, Medical School, University of Zimbabwe, P.O. Box MP 167, Mt. Pleasant, Harare, Zimbabwe; Faculty of Medicine, Departments of Physiology, University of Zimbabwe, P.O. Box MP 167, Mount Pleasant, Harare, Zimbabwe, 333407

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Table 1. Comparison of Body Weight and 5 Day Measures of Food Taken, Fluid Voided, and Urinary Na⁺ and K⁺ Excreted in Untreated (C) and Treated (T) Nondiabetic(n = 8) and STZ-Diabetic Rats over 5 Weeks (n = 8 in Each Group)

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Table 2. Changes in Kidney Weight, Plasma Concentrations of Glucose, Insulin, Na⁺, K⁺, Aldosterone AVP, and Osmolality in Untreated and Treated Nondiabetic and Diabetic Rats After 5 Weeks (n = 8 in All Groups)

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Figure 1. GFR (A), FeK⁺(B) and Fe_Na⁺ (C) rates in nondiabetic and STZ-diabetic control rats and nondiabetic and STZ-diabetic rats administered O. megacantha leaves' extract for 5 weeks vertical bars indicate S.E. of means.

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EFFECTS OF OPUNTIA MEGACANTHA LEAVES EXTRACT ON RENAL ELECTROLYTE AND FLUID HANDLING IN STREPTOZOTOCIN (STZ)-DIABETIC RATS

Table 1. Comparison of Body Weight and 5 Day Measures of Food Taken, Fluid Voided, and Urinary Na⁺ and K⁺ Excreted in Untreated (C) and Treated (T) Nondiabetic(n = 8) and STZ-Diabetic Rats over 5 Weeks (n = 8 in Each Group)

Table 2. Changes in Kidney Weight, Plasma Concentrations of Glucose, Insulin, Na⁺, K⁺, Aldosterone AVP, and Osmolality in Untreated and Treated Nondiabetic and Diabetic Rats After 5 Weeks (n = 8 in All Groups)

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EFFECTS OF OPUNTIA MEGACANTHA LEAVES EXTRACT ON RENAL ELECTROLYTE AND FLUID HANDLING IN STREPTOZOTOCIN (STZ)-DIABETIC RATS

Figures & data

Table 1. Comparison of Body Weight and 5 Day Measures of Food Taken, Fluid Voided, and Urinary Na+ and K+ Excreted in Untreated (C) and Treated (T) Nondiabetic(n = 8) and STZ-Diabetic Rats over 5 Weeks (n = 8 in Each Group)

Table 2. Changes in Kidney Weight, Plasma Concentrations of Glucose, Insulin, Na+, K+, Aldosterone AVP, and Osmolality in Untreated and Treated Nondiabetic and Diabetic Rats After 5 Weeks (n = 8 in All Groups)

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Table 1. Comparison of Body Weight and 5 Day Measures of Food Taken, Fluid Voided, and Urinary Na⁺ and K⁺ Excreted in Untreated (C) and Treated (T) Nondiabetic(n = 8) and STZ-Diabetic Rats over 5 Weeks (n = 8 in Each Group)

Table 2. Changes in Kidney Weight, Plasma Concentrations of Glucose, Insulin, Na⁺, K⁺, Aldosterone AVP, and Osmolality in Untreated and Treated Nondiabetic and Diabetic Rats After 5 Weeks (n = 8 in All Groups)