The Evaluation of Renal Osteodystrophy with Cortical Quantitative Ultrasound at Various Bone Sites

Figures & data

Table 1. Group Characteristics and Biochemical and Bone Quantitative Ultrasound Values (Mean ± SEM)

	Control	CRF	ROD	P
Gender	6M/6F	4M/3F	5M/3F	NS
Age (years)	36.2 ± 2.7	48.9 ± 4.2	36.2 ± 4.4	NS
Creat. Cl.^1 (mL/min)	106.3 ± 4.57	19.5 ± 3.1	NA
s. Ca ^2 + (mmol/L)	1.23 ± 0.01	1.16 ± 0.01	1.17 ± 0.04	NS
s. PO (mg/dL)	3.48 ± 0.15	4.94 ± 0.41	5.86 ± 0.55	**
s. Alk. Phos^1 (U/L)	63.2 ± 5.2	116.2 ± 10.9	165.9 ± 20.22	**#
IPTH^1 (pg/mL)	38.67 ± 4.9	309.7 ± 87.1	792.8 ± 122.2	**
SOS‐TIBIA (m/s)	3941.8 ± 30.2	3945.6 ± 47.8	3596.6 ± 88.5	**#
SOS‐1/3 RAD (m/s)	4074.5 ± 37.5	4065.0 ± 36.3	3664.1 ± 121.9	**#
SOS‐PHAL.X (m/s)	3812.0 ± 35.3	3720.9 ± 52.2	3520.9 ± 55.2	**#

ANOVA with Bonferroni's test or ¹Kruskal‐Wallis (Dunn's) test.

^*(Control vs. CRF).

^**(Control vs. ROD).

^#(CRF vs. ROD) for p < 0.05.

NA—not applicable, NS—not significant.

Table 2. Spearman's correlation coefficients between SOS (m/s) in the midtibia, third distal radius and third proximal phalanx and IPTH (pg/mL) and serum alkaline phosphatase (U/L)

	IPTH	s. Alk. Phos	TIBIA	RAD	PHAL.X
IPTH	–	0.824	(−) 0.398#	(−) 0.660	(−) 0.665
s. Alk. Phos	0.824	–	(−) 0.393#	(−) 0.452#	(−) 0.540
TIBIA	(−) 0.398#	(−) 0.393#	–	0.600	0.384
RAD	(−) 0.660	(−) 0.452#	0.600	–	0.583#
PHAL.X	(−) 0.665	(−) 0.540	0.384	0.583#	–

^*p < 0.001.

^#p < 0.05.