Pulmonary Function in Uremic Patients on Long‐term Hemodialysis

Figures & data

Table 1. Patient Characteristics (Mean ± SD) and the Causes of Chronic Renal Failure

	CRF patients on HD (n = 20)
Age (yrs)	36.7 ± 11.6
Sex (M/F)	12/8
Duration of illness (mo)	86.1 ± 59.4
Duration of HD (mo)	76.3 ± 37.5
Diagnoses
Nephrolithiasis	6
Vesicoureteral reflux	2
Amyloidosis	2
Adult polycystic kidney disease	2
Hypertension	1
Glomerulonephritis	1
Diabetes mellitus	1
Unknown	5

CRF: chronic renal failure; HD: hemodialysis.

Table 2. The Hemogram and Blood Biochemistry Findings for the Group at the Time of the Study

Hemoglobin (g/dL)	11.9 (1.7)
Hematocrit (%)	38 (0.3)
C‐reactive protein (mg/L)	12.6 (11.6)
Blood urea nitrogen (mg/dL)	87.0 (19.5)
Creatinine (mg/dL)	11.0 (2.8)
Parathormone (ng/)	239.0 (230.3)
Albumin (g/dL)	3.8 (0.3)
Sodium (mEq/L)	134.8 (5.3)
Potassium (mEq/L)	5.4 (0.5)
Calcium (mEq/L)	9.0 (0.8)
Phosphorus (mEq/L)	5.4 (1.6)

Values are expressed as mean (SD).

Table 3. The Patients' Chest X‐Ray Findings and Pulmonary Function Test Interpretations from Before the Dialysis Session

Chest X‐ray findings	N
Normal	2
Increased bronchovascular markings	5
Hyperlucency	6
Pulmonary venous congestion	4
Unilateral diaphragmatic elevation	1
Bilateral hilar enlargement	2
PFT interpretation
Normal	12
Obstructive pattern	1
Restrictive pattern	5
Mixed pattern	1
Low DLCO	1
High DLCO	2

DLCO: diffusing capacity of the lung for carbon monoxide.

Table 4. Comparison of the Findings for the PFT Parameters Before and After an HD Session

Parameters	Predialysis (%)	Postdialysis (%)	p
FVC	83.9 ± 13.1	83.2 ± 10.5	NS
FEV1	86.0 ± 13.8	87.6 ± 11.7	NS
FEF25–75	79.3 ± 20.9	83.1 ± 22.3	NS
TLC	107.8 ± 18.0	105.5 ± 14.2	NS
VC	85.5 ± 13.5	86.2 ± 14.0	NS
RV	152.9 ± 48.2	143.9 ± 34.2	NS
DLCO	110.4 ± 26.2	109.0 ± 23.6	NS
PImax	67.4 ± 20.9	60.9 ± 18.0	< 0.05
PEmax	36.3 ± 13.4	33.7 ± 10.9	NS

NS = not significant.

Values are expressed as percent of predicted value ± SD.