Pretransplant Cardiac Investigations in the Irish Renal Transplant Population—The Effectiveness of Our Current Screening Techniques in Predicting Cardiac Events

Figures & data

Table 1. Univariate Cox Proportional Hazard Models

Variables	Hazard ratio	95% C.I.	P value
Sex	0.986	0.54–1.81	0.966
Age	1.91	1.48–2.47	< 0.001
History of MI	2.43	0.99–5.98	0.052
Heart failure	8.22	2.86–23.59	< 0.001
CVA	4.32	1.48–12.36	0.008
Carotid artery disease	3.74	1.13–12.36	0.030
ECG	2.65	1.27–5.54	0.009
ECG—anterior Q wave	8.59	3.8–19.39	< 0.001
ECG—inferior Q wave	2.27	0.87–5.92	0.093
ECG—ST segment change	2.95	1.03–8.44	0.044
Echo ejection fraction	0.97	0.93–1.01	0.098
Echo LVH	0.66	0.24–1.82	0.42
Stress test abnormal	0.99	0.32–3.05	0.991
Angiogram abnormal	5.55	1.15–26.85	0.033
Time on dialysis	1.01	1.00–1.02	0.010
Diabetes (pre‐Tx)	2.03	0.88–4.71	0.098

^*At least 1 abnormal reading of an ECG result for each patient.

Figure 1. Kaplan–Meier survivor functions illustrating effect of abnormal ECG anterior Q result on outcome CABG, MI and death.

Table 2. Multifactorial Cox Proportional Hazards Model with Independently Significant Variables

Variable	Hazard ratio	95% C.I.	P value
Age	1.70	1.24–2.31	0.001
CVA	3.62	1.19–10.99	0.023
ECG—anterior Q wave	5.28	2.14–13.05	< 0.001