Ten Years' Experience in Subtotal Parathyroidectomy of Hemodialysis Patients

Figures & data

Table 1. Symptoms and Signs of SHP Before and After Subtotal Parathyroidectomy.

Symptoms and signs of SHP	Before parathyroidectomy		After parathyroidectomy		p
	No	%	No	%
Pruritus	47	100	9	19	< 0.001
Bone pain	47	100	38	81	< 0.01
Myopathy	42	89	7	15	< 0.001
Joint pain	16	34	11	23	n.s.
Skeletal deformites	11	23	11	23	n.s.
Fractures	9	19	0	0	< 0.01
Periartritis	1	2	0	0	n.s.
Tetiva rupture	1	2	0	0	n.s.

Table 2. Results of Biochemical Analyses Before and 21 Days After Subtotal Parathyroidectomy.

Biochemical parameters	Before parathyroidectomy (mean values ± SD)	After parathyroidectomy (mean values ± SD)	p
Ca (mmol/L)	2.59 ± 0.30	1.96 ± 0.29	< 0.001
PO4 (mmol/L)	2.34 ± 0.54	1.18 ± 0.24	< 0.001
Alkaline phosphatase (U/L)	533.01 ± 405.11	384.12 ± 250.02	< 0.05
IPTH (pg/mL)	1307.77 ± 535.70	39.70 ± 53.16	< 0.001
Urea (mmol/L)	26.92 ± 8.28	26.40 ± 5.84	n.s.
Creatinine (mmol/L)	0.945 ± 0.332	0.929 ± 0.292	n.s.

Figure 1 Distribution of patients according to plasma IPTH levels before subtotal parathyroidectomy.

Table 3. Radiographic Findings in Patients Before Subtotal Parathyroidectomy.

Radiographic findings in SHP	Number of patients	%
Bone cysts	31	66
Subperiostal resorptions	47	100
Intracortical erosions	10	21
Periosteal neostosis	31	66
Osteopenia	14	30
Periarticular or tumoral calcifications	46	98

Figure 2 Changes of calcium, phosphate (a), and alkaline phosphatase (b) serum levels during the first month after subtotal parathyroidectomy.