Long-Term Impact of Chronic Hemodialysis on Glycemic Control and Serum Lipids in Insulin-Treated Type 2-Diabetic Patients

Figures & data

Figure 1. HbA1c and fasting blood glucose (FBG) before and after the start of dialysis.

Table 1 Baseline data of the patients at the start of dialysis

Age (years)	62 ± 9
Sex (m:f)	14:6
BMI	24 ± 2
Diabetes (years)	16 (10–22)
C-peptid basal (ng/mL)	2.1 ± 1.1
HbA1c (%)	7.3 ± 1.2
Fasting blood glucose (mg/dL)	151 ± 47
Serum albumin (g/L)	34.46 ± 6.42
Insulin injections (n/day)	2 (1–3)
Insulin requirement (IU/day)	24 ± 12

Data are given as Mean ± SD or range.

Table 2 HbA1c, fasting blood glucose (FBG), insulin requirement, cholesterol, triglycerides, and incidence of hypoglycemia before and after the start of hemodialysis

	− 12 months	− 6 months	Start of dialysis	+ 6 months	+ 12 months
HbA1c (%)	7.4 ± 1.8	7.3 ± 1.2	7.3 ± 1.3	7.4 ± 1.2	7.3 ± 1.1
FBG (mg/dL)	149 ± 51	147 ± 51	151 ± 46	152 ± 56	150 ± 52
Insulin requirement (IU/day)	26 ± 12	26 ± 10	25 ± 12	23 ± 13	22 ± 13
BMI	24 ± 4	24 ± 3	24 ± 3	23 ± 4	24 ± 3
Cholesterol (mg/dL)	215 ± 59	199 ± 63	190 ± 49	167 ± 62	157 ± 38
Triglycerides (mg/dL)	175 ± 75	169 ± 98	158 ± 83	137 ± 80	148 ± 98
Hypoglycemia (n/patient/month)	0.3	0.4	0.4	0.6	0.6

^*p < 0.05.

Table 3 HbA1c, fasting blood glucose (FBG), and insulin requirement at the start of hemodialysis and after 1 year in patients with high or low residual urine volume (< and > 500 mL urine/day)

	Urine volume
	> 500 mL/day		< 500 mL/day
	Start	After 1 year	Start	After 1 year
HbA1c (%)	7.2. ± 1.4	7.2 ± 1.2	7.3 ± 1.1	7.3 ± 0.8
FBG (mg/dL)	147 ± 81	151 ± 59	154 ± 56	145 ± 47
Insulin requirement (IU/day)	26 ± 12	27 ± 13	24 ± 11	17 ± 8

^*p < 0.05.