Abstract
Microwave-induced synthesis of O′-adamantyl derivatives of AZT, thymidine, 2′-deoxyuridine and uridine was investigated. Contrary to heterocyclus adamantylation of uracil and uridine in trifluoroacetic acid, the microwave-induced reaction provided sugar-substituted compounds.
Acknowledgments
This study was supported by the Foundation for Development Diagnostics and Therapy, Warsaw, Poland. Authors are grateful to Dr. S. J. Chrapusta for useful discussion.