Stereoselective Synthesis of Novel 4′‐Branched and Bicyclo[3.1.0]hexane‐Templated Nucleoside

Abstract

The racemic and stereoselective synthesis of a novel nucleoside 4′‐branched and bicyclo[3.1.0]hexane templated nucleoside 15 was accomplished using a [3,3]‐sigmatropic rearrangement, an intramolecular carbene cycloaddition reaction and a Curtius rearrangement as the key reactions.

Keywords:

• Nucleoside
• Bicyclo[3.1.0]hexane
• [3,3]‐Sigmatropic rearrangement
• Intramolecular carbene cycloaddition