Abstract
A stereoselectively total synthesis of nerylgeraniol-18-oic acid from geraniol was described. The key steps were the iodization- rearrangement of 2, 3-epoxy alcohol 4, stereoselective Claisen rearrangement and Horner-Emmons olefination reaction.
ACKNOWLEDGMENT
The project was financially supported by the Nature Science Foundation of China (200720152).