ABSTRACT
The cleavage of gem-diacetates to aldehydes, a widely used protecting group in organic synthesis, has been achieved for the first time under neutral conditions in aqueous medium using β-cyclodextrin as catalyst. The main advantage of the present methodology is that it can be used with compounds having a variety of functional groups since the cleavage is carriedout under neutral conditions in aqueous medium.
*IICT Communication No. 4655.
ACKNOWLEDGMENTS
MAR and LRR thank CSIR, New Delhi, India, for the award of research fellowships.
Notes
*IICT Communication No. 4655.