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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 32, 2002 - Issue 13
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Original Articles

PREPARATION OF 8-ALKYL 7-(2-IMIDAZOLINYLAMINO)QUINOLINES VIA PALLADIUM MEDIATED ALKYLATIONS

Nick Nikolaides Procter & Gamble Pharmaceuticals, 8700 Mason-Montgomery Road, Mason, OH, 45040, U.S.A.Correspondence[email protected]
,
Sophie E. Bogdan Procter & Gamble Pharmaceuticals, 8700 Mason-Montgomery Road, Mason, OH, 45040, U.S.A.
&
James S. Szalma Procter & Gamble Pharmaceuticals, 8700 Mason-Montgomery Road, Mason, OH, 45040, U.S.A.
Pages 2027-2033 | Received 24 Jul 2001, Published online: 16 Aug 2006
 
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ABSTRACT

A convenient preparation of 8-alkyl substituted 7-(2-imidazolinylamino)quinolines from the corresponding 8-trifluoromethanesulfonates, utilizing palladium cross-coupling reactions is described.

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