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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 32, 2002 - Issue 18
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Original Articles

STEREOSELECTIVE SYNTHESIS OF NEW PHOSPHORYLATED N,N′-DIMETHYLBARBITURIC ACIDS

Issa Yavari Department of Chemistry, University of Tarbit Modarres, P.O. Box 14155–4838, Tehran, Iran
,
Nader Zabarjad-Shiraz Department of Chemistry, University of Tarbit Modarres, P.O. Box 14155–4838, Tehran, Iran
&
Taiebeh Partovi Department of Chemistry, Payam Nor University, Lashgarak, Tehran, Iran
Pages 2763-2769 | Received 19 Jan 2001, Published online: 18 Oct 2011
 
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ABSTRACT

Protonation of the 1 : 1 intermediate produced in the reaction between trimethyl phosphite and dialkyl acetylenedicarboxylates by N,N′-dimethylbarbituric acid leads to dialkyl 2-(dimethyl phosphoryl)-3-(6-methoxy-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-succinates.

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