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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 3
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Original Articles

Synthesis of Some Novel γ-Spiroiminolactones from Reaction of Cyclohexyl Isocyanide and Dialkyl Acetylene Dicarboxylates with 1-Benzylisatin and Tryptanthrine

Javad Azizian Department of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, IranCorrespondence[email protected]
,
Ali R. Karimi Department of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, Iran
&
Ali A. Mohammadi Department of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, Iran
Pages 387-391 | Received 21 Jan 2002, Published online: 17 Aug 2006
 
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Abstract

1:1 intermediate generated by the addition of cyclohexyl isocyanide to dialkyl acetylenedicarboxylates, undergoes facil addition to 1-benzylisatin and tryptantrin to afford highly functionalized novel unsaturated γ-spiroiminolactones in moderate to high yields.

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