Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 6
Submit an article Journal homepage
329
Views
10
CrossRef citations to date
0
Altmetric
Original Articles

A Convenient Procedure for the Synthesis of O6-Benzylguanine Derivatives by Phase Transfer Catalysis

Xuan Liu Departments of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
,
Qi-Huang Zheng Ph.D. Departments of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USACorrespondence[email protected]
,
Gary D. Hutchins Departments of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
,
Xiangshu Fei Departments of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
,
Leonard C. Erickson Departments of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA
,
Kathy D. Miller Departments of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
,
Bruce H. Mock Departments of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
,
Barbara E. Glick-Wilson Departments of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
,
Wendy L. Winkle Departments of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
,
K. Lee Stone Departments of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
&
Kathy A. Carlson Departments of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
 show all
Pages 941-952 | Received 02 Apr 2002, Published online: 17 Aug 2006
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

A convenient procedure by phase transfer catalysis has been developed for the synthesis of O6-BG (1) and its derivatives hydroxymethyl-BG (2a–c), halo-BG (3a–c, 4a–c, 5a–c, 6a–c), methoxy-BG (7), and methyl-BG (8). Compounds 2b, 2c, 4b, 4c, 5b, 5c, 6a, and 6c are new compounds.

Acknowledgments

This work is supported by the National Institutes of Health/National Cancer Institute grant P20CA86350 (to GDH), the Susan G. Komen Breast Cancer Foundation grant IMG 2000 837 (to QHZ), Indiana University American Cancer Society Institutional Grant Committee grant IRG-84-002-17 (to QHZ), and Indiana 21st Century Research & Technology Fund grant (to GDH).

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 422.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.