Abstract
This article reports a short and efficient synthesis of chiral dioxocyclens starting from natural amino acids. Four new chiral dioxocyclens that contain different substituents at the chiral center were obtained. These dioxocyclens could not only be used for chiral recognition, but provide a feasible way for the synthesis of chiral cyclens.
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Acknowledgment
This work was supported by Natural Science Foundation of Hubei Province, China, and partly by a grant from The Education Ministry of China for the visiting scholar to the Key Laboratory of Bioorganic Chemistry and Molecular Engineering at Beijing University.