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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 16
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Original Articles

One-Pot Preparation of Esters from Carboxylic Acids Using the PPh3-CCl3CN System

Doo Ok Jang Department of Chemistry, Yonsei University, Wonju, KoreaCorrespondence[email protected]
,
Dae Hyan Cho Department of Chemistry, Yonsei University, Wonju, Korea
&
Joong-Gon Kim Biotechnology Division, Hanwha Chemical R & D Center, Taejon, Korea
Pages 2885-2890 | Received 20 Nov 2002, Published online: 19 Aug 2006
 
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Abstract

A convenient one-pot process for preparing various esters from carboxylic acids using the Ph3P-CCl3CN has been developed. Racemic α-tocopherol, clofibrate and flavoxate were prepared in high yields using this method.

Acknowledgments

This work was supported by Maeji Institute of Academic Research, Yonsei University.

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