Abstract
The results obtained in the MgBr2‐mediated opening of 2,3‐bifunctionalised aziridines are reported. The study shows that, at least for the Z stereoisomers, the bromide attacks the aziridine ring in the α position to all functional groups considered with high regioselectivity, thus suggesting a strong aptitude for MgBr2 to coordinate a benzyloxy function.
Notes
aCompounds 10, 11a and 11b were obtained as single diastereoisomers. Since the diastereocontrol of the Grignard addition was not our aim, we did not investigate its stereochemistry.