Abstract
Novel 1,3‐dioxane C‐nucleoside analogues of tiazofurin 2‐[2‐(hydroxymethyl)‐1,3‐dioxan‐5‐methyl‐5‐yl] 1,3‐thiazole‐4‐carboxamide, 2‐[2‐(hydroxymethyl)‐1,3‐dioxan‐5‐ethyl‐5‐yl] 1,3‐thiazole‐4‐carboxamide and 2‐[5‐(hydroxymethyl)‐1,3‐dioxan‐5‐methyl‐2‐yl] furan, 2‐[5‐(hydroxymethyl)‐1,3‐dioxan‐5‐methyl‐2‐yl] thiophen have been synthesized from DMPA and DMBA. Their conformational characteristics have been investigated.
Acknowledgment
We are grateful to the National Natural Science Foundation of China (project 20172049) for the financial support.