Abstract
Pyridine, 2-methylpyridine, 3-methylpyridine, 4-methylpyridine, 2,4-dimethylpyridine, 2,6-dimethylpyridine, quinoline, isoquinoline and 2-chloropyridine are readily oxidized to their N-oxides with a solution of trichloroisocyanuric acid, acetic acid, sodium acetate and water in acetonitrile and methylene dichloride in 78%–90% yields.
Acknowledgment
Project 20272043 was supported by The National Nature Science Foundation of China. This work was also supported by The National Nature Science Foundation of Zhejiang Province (201015).