Iodobenzene Diacetate Mediated Solid‐State Synthesis of Heterocyclyl‐1,3,4‐oxadiazoles

Abstract

A simple and efficient method has been developed for the oxidation of various heterocyclyl acylhydrazones 3 with iodobenzene diacetate (IBD) to heterocyclyl‐1,3,4‐oxadiazoles 4 in solid state. The reaction took place at room temperature within few minutes. The products were isolated by simple aqueous work-up in good yields.

Keywords:

• Iodobenzene diacetate
• 1,3,4,‐Oxadiazoles
• Heterocyclyl acylhydrazones
• Solid state synthesis

Acknowledgment

We wish to thank the RSIC, CDRI, Lucknow, India for analytical and spectral data.