Abstract
A mild and efficient method for deprotection of tert‐butyl sulfonamide groups utilizing Sc(OTf)3 as deprotecting reagent has been developed. A variety of tert‐butyl aryl sulfonamides used under these conditions gave the corresponding primary sulfonamides in high yields. The Lewis acid catalyst could be fully recovered and reused with maintained activity after the reactions.
Acknowledgment
We gratefully acknowledge support from the Swedish Foundation for Strategic Research (SSF).