Asymmetric Allylation of Aldimines with Indium and (+)‐Cinchonine

Abstract

By applying indium and allyl bromide, aldimines were converted into homoallyl amines with excellent yields. The addition of (+)‐cinchonine to the reaction mixture yielded enantioselective allylation with 22–44% ee.

Keywords:

• Enantioselective allylation
• indium
• aldimines
• homoallylamines
• chiral ligand

Acknowledgments

This work was supported by the RRC program of MOST/Gyeonggi‐do and partly by BK21 program.