Platelet indices in diabetes mellitus: indicators of diabetic microvascular complications

Figures & data

Figure 1. Peripheral smear from a patient with diabetic complication showing occasional giant platelets (arrow) with normocytic normochromic erythrocytes (Giemsa, ×100).

Table 1. Platelet indices in controls and patients with DM

	MPV (fl, mean±SD)	PDW (%, mean±SD)	P‐LCR (%, mean±SD)
Control (n = 50)	11·42±1·40	15·349±3·14	36·93±9·47
DM (n = 75)	12·08±1·54	17·25±3·56	42·31±10·78
P value (Student’s t‐test)	0·015	0·002	0·004

MPV, mean platelet volume; PDW, platelet distribution width; P‐LCR, platelet‐large cell ratio.

Table 2. Platelet indices in DM patients with and without complications

	MPV (fl, mean±SD)	PDW (%, mean±SD)	P‐LCR (%, mean±SD)
DM without complications (n = 25)	11·77±1·59	15·67±3·77	39·52±12·37
DM with complications (n = 50)	12·25±1·49	18·14±3·14	43·89±9·55
P value (Student’s t‐test)	0·212	0·006	0·096

MPV, mean platelet volume; PDW, platelet distribution width; P‐LCR, platelet‐large cell ratio.

Figure 2. Result of discriminant analysis. Values of discriminant function (x‐axis) were plotted against the number of cases (y‐axis) in each category (black: diabetics without complications; grey: diabetics with complications). Fair separation of both the groups is evident from graph.