Renal function in transfusion-dependent pediatric beta-thalassemia major patients

Figures & data

Table 1. Frequency distribution of serum ferritin values based on GFR changes

Total	Ferritin (ng/ml)		GFR (ml/min/1·73 m^2)
	Abnormal	Normal
11 (7·9)	5 (45·5)	6 (54·5)	<100, n (%)
129 (92·1)	88 (68·2)	41 (31·8)	>100, n (%)
140 (100)	93 (66·4)	47 (33·6)	Total, n (%)

Figure 1. (A) Comparison of urinary NAG activity mean values between two groups. (P = 0·001). (B) The mean age comparison based on urinary NAG enzyme activity (r = 4·66, P<0·001).

Figure 2. The correlation between urinary NAG activity and age (r = 0·351, P<0·001).

Table 2. The frequency distribution of values above normal NAG activity (IU/dl) in age groups of study

Age groups						NAG activity (IU/dl)
Total	16	15	14	13	12
58	4	2	2	5	5	N
100%	6·9%	3·4%	3·4%	8·4%	8·4%	Normal NAG in all patients
41·4%	28·4%	14·3%	14·3%	35·7%	35·7%	Normal NAG in age group
82	10	12	12	9	9	N
100%	12·2%	14·4%	14·4%	11%	11%	Abnormal NAG in all patients
58·6%	71·4%	85·7%	85·7%	64·3%	64·3%	Abnormal NAG in age group
140	14	14	14	14	14	N in groups

Figure 3. Correlation among serum ferritin and urinary NAG enzyme activity (r = 0·11, P = 0·19).

Figure 4. Frequencies of patients with hypercalciuria and urinary NAG activity.

Table 3. Frequencies of patients with high urinary NAG value along with other disorders

Frequency (%)	N	NAG activity>normal
87·8	72	With other disorders
12·2	10	Without other disorders
100	82	Total