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OriginalArticle

Reduced corticosteroid use in adult patients with primary immune thrombocytopenia receiving romiplostim

, , , , , & show all
Pages 274-277 | Published online: 12 Nov 2013

Figures & data

Figure 1. Subject disposition (July 2008). *Reasons for discontinuation from the phase III studies have been reported elsewhereCitation11; †1 subject withdrew consent prior to receiving romiplostim.

Figure 1. Subject disposition (July 2008). *Reasons for discontinuation from the phase III studies have been reported elsewhereCitation11; †1 subject withdrew consent prior to receiving romiplostim.

Figure 2. (A) Corticosteroid use decreased in romiplostim-treated patients during two, 6-month, phase III studies. Percentages calculated from n = number of subjects remaining on study at the start of the relevant time period. (B) Prednisone dose decreased in patients continuing to receive corticosteroids during the phase III studies. N = Number of subjects receiving prednisone-type corticosteroids during the phase III studies; n = number of subjects receiving prednisone-type corticosteroids at specified time point. (C) Corticosteroid use decreased significantly over time in patients treated with romiplostim for up to 3 years in an open-label extension study. n = number of subjects remaining on study.

Figure 2. (A) Corticosteroid use decreased in romiplostim-treated patients during two, 6-month, phase III studies. Percentages calculated from n = number of subjects remaining on study at the start of the relevant time period. (B) Prednisone dose decreased in patients continuing to receive corticosteroids during the phase III studies. N = Number of subjects receiving prednisone-type corticosteroids during the phase III studies; n = number of subjects receiving prednisone-type corticosteroids at specified time point. (C) Corticosteroid use decreased significantly over time in patients treated with romiplostim for up to 3 years in an open-label extension study. n = number of subjects remaining on study.