Thrombophilic gene mutations in children with migraine

Figures & data

Table 1. Characteristics of those with migraine compared with controls

	N* (%)	Gender (M/F)	Age ± SD	↑FVIII (>150 U/ml)	↑FIX (>160 U/ml)
Migraine patients	42	18/24	8.9 ± 4.5	7	5
With aura*	19 (45.2%)	9/10	9.2 ± 3.1	6	1
Without aura*	23 (54.7%)	9/14	7.9 ± 4.7	1	1
Controls	50 (100%)	22/28	10.5 ± 3.2	–	–

*P > 0.05.

Table 2. Rate of genetic mutations in patients and controls, and OR evaluation

	Patients (42)	Controls (50)	OR	CI
FVL*	9 (21.4%)	2 (4%)	7.5	−0.77 + 0.97
F2	5 (11.9%)	3 (6%)	2.1	−0.18 + 0.48
MTHFR*	15 (35.7%)	5 (11.9%)	5	−0.56 + 0.82

*P < 0.05.

Table 3. Rate of thrombophilic factors in migraine sufferers with and without an aura

	Migraine with aura (19)	Migraine without aura (23)
FVL*	7	3
F2*	4	1
MTHFR*	9	6

*P > 0.05.