Table 1. Characteristics of different iron chelators
Figure 1. Major mechanism of iron overload in transfusion-dependent thalassemia. As shown in the figure, the major cause of iron overload in transfusion-dependent thalassemia is the excessive accumulation of transfusional iron that is deposited in the different organs leading to different complications such as heart failure and arrhythmias, liver disease, and endocrine gland dysfunction.
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