Effects of catechin and epicatechin on superoxide dismutase and glutathione peroxidase activity, in vivo

Figures & data

Figure 1. Antioxidant enzymes activities in control and EG. Enzyme activity for GPx is expressed as U/g hemoglobin and for SOD as % inhibition rate. ^aSignificantly different from Day 0, P < 0.05. ^bSignificantly different between groups, P < 0.05. Data are expressed as mean ± SD. GPx, glutathione peroxidase; SOD, superoxide dismutase.

Table 1. TAC and urine MDA concentration in CG and EG

	Group	Day 0	Day 11	Day 22
TAC plasma	CG	56.5 ± 8.1	61.4 ± 9.3	60.2 ± 8.2
(mM alpha-tocopherol)	EG	59.9 ± 8.2	69.0 ± 1.9*,**	60.3 ± 2.6***
TAC RBC	CG	56.7 ± 6.3	61.2 ± 3.2	56.3 ± 6.3
(mM alpha-tocopherol)	EG	56.9 ± 6.4	59.0 ± 1.5	53.8 ± 1.1***
TAC urine	CG	57.4 ± 4.0	61.1 ± 2.4**	61.7 ± 1.5**
(mM alpha-tocopherol)	EG	56.8 ± 3.7	73.1 ± 2.1*,**	76.7 ± 1.5 *,**
MDA urine	CG	1.3 ± 0.2	1.2 ± 0.3	1.1 ± 0.3
(μM)	EG	1.3 ± 0.2	1.3 ± 0.3	1.4 ± 0.4

*Significantly different from Day 0, P < 0.05.

**Significantly different between groups, P < 0.05.

***Significantly different between Days 11 and 22, P < 0.05.

Data are expressed as mean ± SD. RBCs, red blood cells; TAC, total antioxidant capacity; MDA, malonaldehyde.

Table 2. Food consumption, water intake, urine output, and fecal weight in the CG and EG during the experimental period (Days 0–21)

	Group	Days 0–10	Days 12–21
Food consumption (g)	CG	11.6 ± 1.3	11.5 ± 0.9
	EG	12.6 ± 1.2	13.6 ± 0.8
Water intake (ml)	CG	18.4 ± 2.1	22.4 ± 5.0
	EG	18.3 ± 1.8	19.9 ± 1.6
Urine output (ml)	CG	4.5 ± 1.0	9.4 ± 3.9
	EG	5.8 ± 1.2*	5.6 ± 0.7*
Fecal weight (g)	CG	2.0 ± 0.3	2.3 ± 0.5
	EG	2.9 ± 0.3*	3.0 ± 0.2*

*Significantly different between groups, P < 0.05. Data are expressed as mean ± SD.

Figure 2. Relationship between SOD and GPx activity in the EG. The SOD activity accounts for almost 40% of the variability in GPx activity (and vice versa).