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HEMATOLOGICAL MALIGNANCY

Meta-analysis of all-trans retinoic acid-linked arsenic trioxide treatment for acute promyelocytic leukemia

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Figures & data

Table 1. Details of included studies

Table 2. Characteristics of included studies comparing ATRA + ATO with ATRA-alone and ATO-alone, ATRA with ATO in the treatment of APL

Figure 1. Forest plots of the CR rate (A), gastrointestinal complications (B) cutaneous reaction (C), encephalalgia (D), and liver injury (E) in ATRA + ATO therapy and ATRA therapy for APL. RR, relative risk; CI, confidence interval.

Figure 1. Forest plots of the CR rate (A), gastrointestinal complications (B) cutaneous reaction (C), encephalalgia (D), and liver injury (E) in ATRA + ATO therapy and ATRA therapy for APL. RR, relative risk; CI, confidence interval.

Figure 2. The meta-analysis of complications in ATRA + ATO therapy and ATO therapy for APL; cutaneous reaction (A), gastrointestinal complications (B), encephalalgia (C), liver injury (D). RR, relative risk; CI, confidence interval.

Figure 2. The meta-analysis of complications in ATRA + ATO therapy and ATO therapy for APL; cutaneous reaction (A), gastrointestinal complications (B), encephalalgia (C), liver injury (D). RR, relative risk; CI, confidence interval.

Figure 3. Comparison of CR rate (A) and liver injury (B) between ATRA group and ATO group. RR, relative risk; CI, confidence interval.

Figure 3. Comparison of CR rate (A) and liver injury (B) between ATRA group and ATO group. RR, relative risk; CI, confidence interval.

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