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STEM CELL TRANSPLANTATION

Association between NOD2 single nucleotide polymorphisms and Grade III–IV acute graft-versus-host disease: A meta-analysis

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Figures & data

Figure 1. The study selection flow chart according to PRISMA.

Figure 1. The study selection flow chart according to PRISMA.

Table 1. Summary of studies that have examined the association between NOD2/CARD15 SNPs and aGVHD

Table 2. The results of this meta-analysis

Figure 2. Forest plot for risk of Grade III–IV aGVHD associated with pairs NOD2 SNPs in all studies (A) and in the Caucasian population (B). OR, odds ratio; CI, confidence interval.

Figure 2. Forest plot for risk of Grade III–IV aGVHD associated with pairs NOD2 SNPs in all studies (A) and in the Caucasian population (B). OR, odds ratio; CI, confidence interval.

Figure 3. Subgroup analysis of pairs NOD2 SNPs and Grade III–IV aGVHD risk in IS (A) and MUD (B). OR, odds ratio; CI, confidence interval.

Figure 3. Subgroup analysis of pairs NOD2 SNPs and Grade III–IV aGVHD risk in IS (A) and MUD (B). OR, odds ratio; CI, confidence interval.

Figure 4. Pairs NOD2 SNPs and Grade III–IV aGVHD risk in T-cell depletion (A) and gut decontamination (B) patients. OR, odds ratio; CI, confidence interval.

Figure 4. Pairs NOD2 SNPs and Grade III–IV aGVHD risk in T-cell depletion (A) and gut decontamination (B) patients. OR, odds ratio; CI, confidence interval.

Figure 5. Funnel plot with pseudo 95% confidence limits about pairs NOD2 SNPs and Grade III–IV aGVHD.

Figure 5. Funnel plot with pseudo 95% confidence limits about pairs NOD2 SNPs and Grade III–IV aGVHD.

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