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Research Article

Glutathione supplementation suppresses muscle fatigue induced by prolonged exercise via improved aerobic metabolism

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Figures & data

Figure 1 The effect of glutathione on blood glucose (A), NEFA (B), and intermuscular pH (C) in sedentary and exercised mice. Values are provided as mean ± SE. *p < 0.05, **p < 0.01, ***p < 0.001.

Figure 2 The effect of glutathione on PGC-1α (A), AMPK (B) and mtDNA (C) levels in skeletal muscle in sedentary mice. Values are provided as mean ± SE. *p < 0.05.

Figure 3 The effect of glutathione on blood glucose (A) and lactate (B) level in humans. Values are provided as the mean ± SE. *p < 0.05, **p < 0.01 vs. Rest.

Figure 4 The effect of glutathione on plasma ethanol-soluble (A) and protein-bound (B) glutathione level in humans. Values are provided as the mean ± SE. *p < 0.05.

Figure 5 The effect of glutathione on heart rate (A) and the rating of perceived exertion (B) level in in humans. Values are provided as the mean ± SE. *p < 0.05 vs. placebo.

Table 1 Psychological examination after exercise

Supplemental material

Images of western blotting for PGC-1α, AMPK, and β-actin in control (C) and glutathione (G) groups.

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