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Research Article

Effects of Methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon: a double-blind, randomized, placebo-controlled trial

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Figures & data

Table 1 Participant Characteristics

Fig. 1 Recruitment and Enrollment. Flow chart for participant recruitment and enrollment

Table 2 Post-exercise outcomes compared to baseline

Fig. 2 Muscle and Joint Pain. Reported pain levels (in millimeters of VAS) at each time point for Muscle pain and Joint pain. Each graph shows mean outcomes for placebo and MSM groups at each timepoint. Error bars indicate 95% confidence intervals. Results were controlled for baseline

Table 3 Between-group comparisons

Fig. 3 Oxidative Stress. Serum oxidative stress levels, measured in levels of 8-OHdG and MDA. Each graph shows mean outcomes for placebo and MSM groups at each timepoint. Error bars indicate 95% confidence intervals. Results were controlled for baseline

Fig. 4 Muscle Damage. Serum levels of LDH and logarithmically adjusted CK – indicators of muscle damage. Each graph shows mean outcomes for placebo and MSM groups at each timepoint. Error bars indicate 95% confidence intervals. Results were controlled for baseline