https://orcid.org/0000-0003-3999-9395
Figures & data
Fig. 1 Experimental Design. Each subject visited the laboratory one week apart. Subjects were supplemented with either 8 g of citrulline malate or a placebo. The German Volume Training (GVT) was performed utilising an isokinetic single leg, leg extension protocol, 10 sets of 10 repetitions at 80% 1 RM (obtained during baseline testing), with 1 min rest between sets
Table 1 Baseline subject characteristics
Table 2 Subjects 24 h dietary intake preceding German volume training for both treatment arms
Fig. 2 Mean Number of Repetitions Performed Per Set, with and without Citrulline Malate Supplementation. Means were compared using a repeated measures ANOVA, No significant difference was detected between placebo and treatment P = 0.33, or treatment × sets P = 0.34. Repetitions significantly decreased over the ten sets P = 0.01, e.g. subjects performed significantly less repetitions as they progressed from set 1 to set 10 irrespective of treatment. Error bars indicate standard error of the mean
Table 3 Maximal voluntary force production (N) at baseline and following German volume training with either citrulline malate or placebo
Table 4 Ratios of citrulline to malate from different supplement companies with purported 2:1 ratios measured by nuclear magnetic resonance spectroscopy
Fig. 3 Quadriceps Muscle Soreness Over Time following German Volume Training with, and without Citrulline Malate. Means were compared using a repeated measures ANOVA. There was a significant difference between treatment, time and treatment × time P < 0.01. i.e. significantly more muscle soreness was observed in the citrulline malate treatment compared to the placebo treatment over time. A Post Hoc was performed using a pairwise comparison and Bonferroni adjustment. * symbols indicate significant difference between pre and 72 h time point with. Error bars indicate standard error of the mean, h, hours
