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Commentary

Evaluation of the prophylaxis and treatment of COVID-associated coagulopathy

ORCID Icon, &
Article: 73 | Received 22 Jul 2020, Accepted 07 Oct 2020, Published online: 04 Dec 2023

Figures & data

Fig. 1 Characteristic features of COVID-19-associated coagulopathy

Fig. 1 Characteristic features of COVID-19-associated coagulopathy

Fig. 2 Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of different D-dimer cut-off levels for predicting VTE in COVID-19 patients [Citation19]

Fig. 2 Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of different D-dimer cut-off levels for predicting VTE in COVID-19 patients [Citation19]

Fig. 3 ISTH algorithm for management of coagulopathy in COVID-19 [Citation33]. Algorithm for the management of coagulopathy in COVID‐19 based on simple laboratory markers. * The list of markers is given in decreasing order of importance. ** Performing fibrinogen assays may not be feasible in many laboratories, but monitoring the levels can be helpful after patient admission. *** Although a specific cut‐off cannot be defined, a three‐ to four‐fold increase in D‐dimer values may be considered significant. Anyone of the values in this table may be regarded as significant

Fig. 3 ISTH algorithm for management of coagulopathy in COVID-19 [Citation33]. Algorithm for the management of coagulopathy in COVID‐19 based on simple laboratory markers. * The list of markers is given in decreasing order of importance. ** Performing fibrinogen assays may not be feasible in many laboratories, but monitoring the levels can be helpful after patient admission. *** Although a specific cut‐off cannot be defined, a three‐ to four‐fold increase in D‐dimer values may be considered significant. Anyone of the values in this table may be regarded as significant

Fig. 4 Emory protocol—April 22, 2020

Fig. 4 Emory protocol—April 22, 2020

Fig. 5 Cleveland Clinic thrombosis risk assessment [Citation36]

Fig. 5 Cleveland Clinic thrombosis risk assessment [Citation36]

Fig. 6 Coagulation cascade

Fig. 6 Coagulation cascade

Availability of data and materials

Data sharing is not applicable to this article, as no datasets were generated or analyzed during the current study.